E-ISSN 2090-0503 | ISSN 1687-7497
 

Original Research 


Synthesis, characterization and biological activities of copper nanoparticles

Eman Abdullah M. Ali.

Abstract
Nanotechnology is the most advanced research area in the present era. Copper nanoparticles displayed a significant role in many biological fields. The aim of the present study is to synthesize, characterize and study the biological activities of copper nanoparticles. Copper nanoparticles were produced from copper nitrate by chemical reduction method using isopropyl alcohol and cetyl trimethylammonium bromide (CTAB). Synthesized particles were characterized by fourier transform infrared (FTIR) spectrophotometer and transmission electron microscopic (TEM) analysis. Spherical particles were produced with size range 5-13 nm. Antimicrobial activities of both copper nanoparticles and copper nitrate precursor were tested against Aspergillus flavus, Aspergillus fumigatus, Aspergillus niger, Candida albicans, Penicillium expansum, Staphylococcus aureus, Streptococcus faecalis, Streptococcus mutans, Escherichia coli, Neisseria gonorrhoeae and Pseudomonas aeruginosa. Both copper nanoparticles and copper nitrate precursor showed higher antibacterial activities than antifungal activities. Copper nanoparticles and copper nitrate precursor showed antioxidant activity relatively close to each other, with efficient antioxidant activity reached to 95.42% at 500 g/ml of copper nanoparticles. Copper nanoparticles revealed higher significant cytotoxic effects than copper nitrate precursor. Production of copper nanoparticles by using chemical reduction method was simple, unexpensive and fast. Copper nanoparticles exhibited significant biological activities.

Key words: Copper nanoparticles, FTIR, TEM, Antimicrobial activity, Antioxidant activity, Cytotoxicity


 
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How to Cite this Article
Pubmed Style

Ali EAM, . Synthesis, characterization and biological activities of copper nanoparticles. Egypt. J. Exp. Biol. (Bot.). 2019; 15(2): 393-402. doi:10.5455/egyjebb.20191208055126


Web Style

Ali EAM, . Synthesis, characterization and biological activities of copper nanoparticles. http://www.egyseb.net//?mno=77143 [Access: October 30, 2020]. doi:10.5455/egyjebb.20191208055126


AMA (American Medical Association) Style

Ali EAM, . Synthesis, characterization and biological activities of copper nanoparticles. Egypt. J. Exp. Biol. (Bot.). 2019; 15(2): 393-402. doi:10.5455/egyjebb.20191208055126



Vancouver/ICMJE Style

Ali EAM, . Synthesis, characterization and biological activities of copper nanoparticles. Egypt. J. Exp. Biol. (Bot.). (2019), [cited October 30, 2020]; 15(2): 393-402. doi:10.5455/egyjebb.20191208055126



Harvard Style

Ali, E. A. M. & (2019) Synthesis, characterization and biological activities of copper nanoparticles. Egypt. J. Exp. Biol. (Bot.), 15 (2), 393-402. doi:10.5455/egyjebb.20191208055126



Turabian Style

Ali, Eman Abdullah M., and . 2019. Synthesis, characterization and biological activities of copper nanoparticles. THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Botany), 15 (2), 393-402. doi:10.5455/egyjebb.20191208055126



Chicago Style

Ali, Eman Abdullah M., and . "Synthesis, characterization and biological activities of copper nanoparticles." THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Botany) 15 (2019), 393-402. doi:10.5455/egyjebb.20191208055126



MLA (The Modern Language Association) Style

Ali, Eman Abdullah M., and . "Synthesis, characterization and biological activities of copper nanoparticles." THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Botany) 15.2 (2019), 393-402. Print. doi:10.5455/egyjebb.20191208055126



APA (American Psychological Association) Style

Ali, E. A. M. & (2019) Synthesis, characterization and biological activities of copper nanoparticles. THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Botany), 15 (2), 393-402. doi:10.5455/egyjebb.20191208055126