E-ISSN 2090-0503 | ISSN 1687-7497
 

Original Research 


Long-term use of Spirulina platensis, Ganoderma lucidum, silymarin and green tea can reduce the viral load and side effects of HCV patients

Abd El-Raheem Ramadan El-Shanshoury, Wagih A. El Shouny, Hegazy M. Hegazy, Maha A. F. Khalil, Emad M. S. Elfeky, Mohammed A. Eid.

Abstract
The present study aimed to evaluate the impact of the long-term treatment with a combination of Spirulina platensis (Sp), Ganoderma lucidum (Gd), silymarin (Sil), and green tea (Gt) in HCV patients. Forty-five adult males (M) and females (F) HCV patientsí elderly 40 to 65 were involved in this observational study. HCV patients were divided into 4 subjects; subject-1 included 15 HCV patients (10M and 5F) and was administered with INF/Rib for 12 months. Subject-2 contained 7M plus 3F dealt with Sp, Sil, and Gt. 10 HCV patients concerned in Subject-3 (7M and 3F) and handled with Sp, Sil, Gd, and Gt. Subject-4 covered 10 HCV patients (6M and 4F) who received Sp, Gd, and Gt. The combined treatments of Sp, Sil, Gd, and Gt were administered orally for 12 months in doses of 20, 4, 0.8, and 6 mg/kg, respectively. Viral load, hematological parameters, liver, kidney functions, and blood glucose were determined in all HCV patients. The results confirmed that each treatment condition did no longer dispose of viral particles in HCV patients contrasted to patients treated with INF/Rib. Furthermore, in subject three, the treatment with Sp, Sil, Gd, and Gt caused a potential decrease in the viral load, progression of hematological pictures, decreased levels of liver enzymes (ALT, AST), and urea. In conclusion, these treatments could be used as adjunct to conventional treatment regimens.

Key words: Spirulina platensis, Ganoderma lucidum, Silymarin, Green tea, Viral load, Hepatitis C virus.


 
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How to Cite this Article
Pubmed Style

El-Shanshoury AER, Shouny WAE, HMH, MAFK, Elfeky EMS, Eid MA, . Long-term use of Spirulina platensis, Ganoderma lucidum, silymarin and green tea can reduce the viral load and side effects of HCV patients. Egypt. J. Exp. Biol. (Bot.). 2021; 17(1): 67-75. doi:10.5455/egyjebb.20210816021936


Web Style

El-Shanshoury AER, Shouny WAE, HMH, MAFK, Elfeky EMS, Eid MA, . Long-term use of Spirulina platensis, Ganoderma lucidum, silymarin and green tea can reduce the viral load and side effects of HCV patients. http://www.egyseb.net//?mno=111521 [Access: August 30, 2021]. doi:10.5455/egyjebb.20210816021936


AMA (American Medical Association) Style

El-Shanshoury AER, Shouny WAE, HMH, MAFK, Elfeky EMS, Eid MA, . Long-term use of Spirulina platensis, Ganoderma lucidum, silymarin and green tea can reduce the viral load and side effects of HCV patients. Egypt. J. Exp. Biol. (Bot.). 2021; 17(1): 67-75. doi:10.5455/egyjebb.20210816021936



Vancouver/ICMJE Style

El-Shanshoury AER, Shouny WAE, HMH, MAFK, Elfeky EMS, Eid MA, . Long-term use of Spirulina platensis, Ganoderma lucidum, silymarin and green tea can reduce the viral load and side effects of HCV patients. Egypt. J. Exp. Biol. (Bot.). (2021), [cited August 30, 2021]; 17(1): 67-75. doi:10.5455/egyjebb.20210816021936



Harvard Style

El-Shanshoury, A. E. R., Shouny, W. A. E., , H. M. H., , M. A. F. K., Elfeky, E. M. S., Eid, M. A. & (2021) Long-term use of Spirulina platensis, Ganoderma lucidum, silymarin and green tea can reduce the viral load and side effects of HCV patients. Egypt. J. Exp. Biol. (Bot.), 17 (1), 67-75. doi:10.5455/egyjebb.20210816021936



Turabian Style

El-Shanshoury, Abd El-Raheem Ramadan, Wagih A. El Shouny, Hegazy M. Hegazy, Maha A. F. Khalil, Emad M. S. Elfeky, Mohammed A. Eid, and . 2021. Long-term use of Spirulina platensis, Ganoderma lucidum, silymarin and green tea can reduce the viral load and side effects of HCV patients. THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Botany), 17 (1), 67-75. doi:10.5455/egyjebb.20210816021936



Chicago Style

El-Shanshoury, Abd El-Raheem Ramadan, Wagih A. El Shouny, Hegazy M. Hegazy, Maha A. F. Khalil, Emad M. S. Elfeky, Mohammed A. Eid, and . "Long-term use of Spirulina platensis, Ganoderma lucidum, silymarin and green tea can reduce the viral load and side effects of HCV patients." THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Botany) 17 (2021), 67-75. doi:10.5455/egyjebb.20210816021936



MLA (The Modern Language Association) Style

El-Shanshoury, Abd El-Raheem Ramadan, Wagih A. El Shouny, Hegazy M. Hegazy, Maha A. F. Khalil, Emad M. S. Elfeky, Mohammed A. Eid, and . "Long-term use of Spirulina platensis, Ganoderma lucidum, silymarin and green tea can reduce the viral load and side effects of HCV patients." THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Botany) 17.1 (2021), 67-75. Print. doi:10.5455/egyjebb.20210816021936



APA (American Psychological Association) Style

El-Shanshoury, A. E. R., Shouny, W. A. E., , H. M. H., , M. A. F. K., Elfeky, E. M. S., Eid, M. A. & (2021) Long-term use of Spirulina platensis, Ganoderma lucidum, silymarin and green tea can reduce the viral load and side effects of HCV patients. THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Botany), 17 (1), 67-75. doi:10.5455/egyjebb.20210816021936